Journal of Clinical And Community Medicine

No validated micro(mi)RNA diagnostic test currently exist for the diagnostic screening of colon cancer (CC). MiRNAs are good candidates for markers for cancer diagnosis, prognosis or response to therapy. Profiles of miRNA expression differ between normal tissues and tumor types, and evidence suggests that miRNA expression profiles cluster similar tumor types together more accurately than expression profiles of protein-coding mRNA genes. A small number of miRNAs can differentiate cancer from normal, and miRNAs in stool remain mostly intact for detection We first carried a microarray study on immunocaptured stool colonocytes on 15 subjects and selected a panel of 14 preferentially expressed mature miRNAs associated with colon cancer (12 Up-Regulated, miR-19a, miR-20a, miR-21, miR-31, miR-34a, miR-96, miR-106a, miR-133a, miR-135b, miR-206, miR-224 and miR-302; and 2 Down-Regulated, miR-143 and miR-145). Read more about articles: https://lupinepublishers.com/clinical-community-medicine/ful

Clinical entities known to mimic the presentation of pulmonary embolism (PE) include pneumonia, asthma, bronchitis, chronic obstructive airway disease (COPD) flare, congestive heart failure, acute myocardial infarction, primary pulmonary artery sarcoma, and nephrolithiasis. Only two cases of vertebral osteomyelitis mimicking PE are found in the literature. We report a rare case of lumbar vertebral osteomyelitis presenting with pleuritic chest pain and shortness of breath, and therefore causing delayed diagnosis. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/vertebral-osteomyelitis-masquerading-as-pulmonary-embolism.ID.000123.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:ruyezt5ZtCIC