Journal of Clinical And Community Medicine

A comparative study of Enzyme linked immunosorbent assay (ELISA) and rapid test screening method on HIV, HBV, HCV and syphilis among voluntary donors was investigated on 350 subjects in Owerri. They were 250 males and 100 females, all ranging from the age of 21-50 years. Transfusion transmissible infections (TTIS) are the major problem associated with blood transfusion. Accurate estimates of risk of TIIS are essential for monitoring the safety of blood supply and evaluating the efficacy of currently employed screening procedures for immunodeficiency virus (HIV 1 and 2) hepatitis B virus (HBV), hepatitis C virus (HVC) and syphilis using both enzyme linked immunosorbent assay (ELISA) and rapid test screening method. Read more about this article: https://lupinepublishers.com/clinical-community-medicine/fulltext/comparative-study-of-enzyme-linked-immunosorbent-assay-elisa-and-rapid-test-screening-methods-on-hiv.ID.000137.php Read more  Lupine Publishers Google Scholar   articles: ...

In the last decade, an increase in Human Immunodeficiency Virus (HIV) infection, the latest global threat paved way for the increase in new emerging and re-emerging sexually transmitted diseases (STD`s) especially in Africa where health care policies are non-existent or not workable. Syphilis is a sexually transmitted disease caused by a spirochete  Treponema pallidum . STD`s like syphilis remains an emerging threatening disease which can go unnoticed because of the asymptomatic nature of its tertiary stage. Several occupational groups, lifestyle factors, and age are at risk of being infected and can even be transferred congenitally which poses a threat to the unborn child. Read more about this article: https://lupinepublishers.com/clinical-community-medicine/fulltext/seroprevalence-of-treponema-pallidum-hiv-co-infection-cognitive-effects-and-risk-variables.ID.000136.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=v...

Hemoglobin disorders are autosomal recessively inherited, genetically transmitted monogenic blood defects, world-wide highly prevalent in tropical regions, and causing the major public health challenges in central India. In view of credit for the 2nd highest infant mortality rate (IMR) in Madhya Pradesh (70 per thousand live-births in the year 2010), it seems, therefore, carrier couples of the hemoglobinopathies might be one of the contributing factors for the high IMR in central India. Read more about this article:  https://lupinepublishers.com/clinical-community-medicine/fulltext/hemoglobin-disorders-and-scenario-of-reproductive-medicine-in-central-india.ID.000134.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:rmuvC79q63oC

There was a clear distinction between healthy reference values measured in healthy populations or individuals and patient reference values measured in patients having various diseases. It is now commonly accepted that reference values describe fluctuations observed in healthy populations or individuals, which makes the definition of health or characterization of health status a critical step. Read more about this article:  https://lupinepublishers.com/clinical-community-medicine/fulltext/reference-intervals-ris-normal-values-health-status-and-clinical-decision-limits.ID.000133.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:_axFR9aDTf0C

Related actual COVID -19 pandemic it is possible to verify that not all countries in the world choose the same strategy to reduce health and economic severe consequences. Following the more effectives strategy make possible a rapid and useful come back to the situation pre-pandemia. Some management instrument makes possible to avoid worse situations. In this work some instruments are analyzed to produce a global conclusion related the topics related. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/covid-19-pandemic-and-the-management-strategy-for-business-and-economy.ID.000129.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:hCrLmN-GePgC

No validated micro(mi)RNA diagnostic test currently exist for the diagnostic screening of colon cancer (CC). MiRNAs are good candidates for markers for cancer diagnosis, prognosis or response to therapy. Profiles of miRNA expression differ between normal tissues and tumor types, and evidence suggests that miRNA expression profiles cluster similar tumor types together more accurately than expression profiles of protein-coding mRNA genes. A small number of miRNAs can differentiate cancer from normal, and miRNAs in stool remain mostly intact for detection We first carried a microarray study on immunocaptured stool colonocytes on 15 subjects and selected a panel of 14 preferentially expressed mature miRNAs associated with colon cancer (12 Up-Regulated, miR-19a, miR-20a, miR-21, miR-31, miR-34a, miR-96, miR-106a, miR-133a, miR-135b, miR-206, miR-224 and miR-302; and 2 Down-Regulated, miR-143 and miR-145). Read more about articles: https://lupinepublishers.com/clinical-community-medicine/ful...

The purpose of the study was to identify emotion problems of psychologists who committed suicide through the material they have written. Convenient purposive sampling was used to identify and select the sample. Books that were freely available was preferred. Books written by Silberer [1] and Gardner [2] were chosen as sample, both of them belonged to different time frame and school of thoughts. Key word analysis along with interpretive content analysis was used to identify emotional problems expressed by these authors in the written content. Subjective knowledge was coded as neutral, only opinion-based line were coded. Key word analysis showed more prevalence of positive words and mild feeling words in the content. Interpretive content analysis showed the presence of psychological issues like depression, anxiety, anger, frustration, guilt, grief, uncertainty, high self-esteem, and stress. Common patterns emerged were extreme point of view in generic conduct of society or in overall opi...

Late preterm infants are those born between 34 to 36 weeks and 6 days of gestation. The incidence of these premature babies reaches up to 20% between 1990 and 2006 in the United States. Although these premature babies may be born with similar size to term children, they are less mature and suffer from greater morbidity and mortality. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/benefits-of-breast-milk-in-extreme-premature-newborns-clinical-case.ID.000119.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:xtoqd-5pKcoC

A standardized patient is a modern educational method that can develop clinical decision making. Educational professionals believe in the field of medicine the use of standardized patient is a way to complete Educational experiences of Medical Group students. Therefore, this study aimed to determine the promotion of nursing students’ learning using the standardized patient method in the patient education lesson. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/improving-nursing-students-learning-using-the-standardized-patient-method-in-patient-education-lesson.ID.000118.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:Dip1O2bNi0gC

This clinical and psychopathological research is conducted after 40 years of experience in pedo- psychiatric practice, notably in institutional care and as a judicial and administrative expert. In a changing society, even in mutation, both in socio-familial and economical and technological fields, the conditions of exchange, the aim or even the sense of the work- also although human relationships, existential modalities - can cause stumbling blocks on the construction or building of identity. The children, the teenagers, the great adolescents are confronted with new ethical and deontological standards and benchmarks, attractive requests, while they are at the age of experiences, even adventures, in case of failures of the symbolic and poverty of the imaginary. So this way, they can be brought to inappropriately rushing into real through actions sometimes incongruous, transgressive, even deviant, sometimes deadly, all the more so as the latency phase has shrunk a lot, or even faded and ...

The gastric ulcer is epidemic disease in many countries the main cause of the disease is helicobacter pylori which transfers by polluted foods. Many protocols and guidelines for the treatment and the most common guidelines is triple therapy Amoxicillin, Clarithromycin and proton pump inhibitors, but now the resistant to this protocol due to irrational use of the antibiotics. The study was done on the Helicobacter pylori by Kirby-Bauer sensitivity Test method which clarify that one of the components of the triple therapy clarithromycin, which failed to pass the test which indicates the retarding in the recovery to H. Pylori that open road to put new guidelines for H. Pylori especially in countries widely and irrationally use antibiotics. The study recommended that to put new guidelines and studies about the growing of resistant to antibiotics. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/irrational-use-of-the-treatment-for-h-pylori-guidelin...

While some of scholars believe that combining adult and adolescent suicidal behavior findings can result in misleading conclusions, some of researchers have stated that suicidal behavior may be a different phenomenon in adolescents than in adults. Hence, in the present study, the clinical profile of suicidal behavior among adult and child & adolescent psychiatric inpatients, has been compared with each other, to assess their resemblances or variances, in a non-western, local patient population. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/contrast-between-adult-and-adolescent-suicidal-behavior-probe-in-psychiatric-inpatients.ID.000115.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:i2xiXl-TujoC

Our special interest in the study of the role of amino acids in the pathogenesis, prevention and treatment of atherosclerosis and its accompanying cardiovascular pathology in circulatory failure is due to several reasons. So, atherosclerosis is characterized not only by disturbances in the metabolic flows of carbohydrate (inhibition of gluconeogenesis and activation of glycolysis), lipid (activation of lipolysis, ketosis), but also protein (protein and hypoalbuminemia), hyperglobulinemia and negative nitrogen balance) [1-18]. There is comparatively little data in the available literature on changes in the spectrum (pool, fund) of free plasma amino acids against the background of atherosclerosis. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/amino-acid-imbalance-in-atherosclerosis.ID.000114.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-...

Sameer Calghatgi (2013) demonstrated that mitochondria, a primitive endosymbiotic bacteria, related to extant SARII marine bacteria and Rickettsias, in eukaryotes is responsible for oxidative phosphorylation (OP) and ATP and NAD production, when exposed to clinically equivalent doses of antibiotics that target bacteria (cipromycin, ampicillin, kanamycin), exhibited a decline in glutathione titre, an increase in reactive oxygen (ROS) and an increase in lipid peroxide. The antibiotics tested were from 3 categories; quinolonesorganofluorine compounds such as ofloxacin, norfloxacin (noroxin), ciprofloxacin (Cipro), moxifloxacin (Avelox); aminoglycosides-Gentamicin, amikacin which create holes in the outer cell wall of bacteria suggesting mitochondria might be at risk of similar damage[1] β-lactams or penicillin derivatives such as cephalosporins, monobactams, carbapenems, carbapenems that inhibit cell wall synthesis in bacteria and by inference mitochondrial reproduction. Read more about a...

Tachypnea is a well-known clinical symptom. Specific electrocardiographic T-wave changes during tachypnea are a crucial point in the decision. The new sign is a constellation of the T- waves changes in special leads. There are three types were prescribed. The types have classified either base on an interaction between lead I and II, or aVL and aVR or V1 and V2. Hyperventilation syndrome, left bundle branch block, left ventricular strain, and Wolff-Parkinson-White syndrome was common inducers. Read more about articles: https://lupinepublishers.com/clinical-community-medicine/fulltext/connected-aircraft-squadron-electrocardiographic-sign-yasser-sign-an-index-for-tachypnea.ID.000112.php Read more  Lupine Publishers Google Scholar   articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&cstart=20&pagesize=80&citation_for_view=vfbCW-wAAAAJ:-FonjvnnhkoC

Eczema is skin very serious skin disease of skin inflammation that causes the skin to become itchy, red, swollen and painful. It is also called as Atopic dermatitis usually developed on early stage of children in India 10 million cases per year is observed. Atopic dermatitis is also passed one general to next generation & the treatment is self-diagnosable lab test or Imaging not required. Eczema developed with allergies such as asthma, cold sores etc. It usually starts on the face followed by the hands and feet. Older children tend to be affected in the elbow and knee creases, neck, wrists, ankles and feet. Genetic mutations that affect the skin’s barrier function Immune system dysfunction causing an unwanted inflammatory response in the skin. Certain substances or conditions called trigger factors can cause eczema to flare (ie: become worse). Trigger including such as Irritants such as soaps and detergents, wool, skin infections, dry skin, low humidity, heat, sweating or emotional...

Globally infertility is evidently recognized as of public health concern especially in African countries. In African societies human reproduction is highly valued and inability to conceive is considered a personal tragedy and a curse for couples, impacting on the entire family and local community. Stem cells are the new technique in this era against many diseases and disorders. The paper reviewed scientific related literature on the effectiveness of stem cells therapeutics in the management of infertility and its associated challenges especially in African society.  Various studies employed nonrandomized clinical trials on evaluating the effectiveness of stem cells therapy in the management of infertility and its associated challenges. Read more about articles:  https://lupinepublishers.com/clinical-community-medicine/fulltext/stem-cells-therapeutics-for-infertility-the-future-perspectives-in-african-countries.ID.000110.php Read more  Lupine Publishers Google Scholar arti...

The study was carried out in 40 patients of different age groups and their breaths were exhaled. These breaths were analyzed by the use of sensors which were basically functionalized with gold nanoparticles. Sensitivity and specificity with relation to CKD patient classification according to estimated glomerular filtration rate were determined using cross-validation. The medicine was induced after the proper analysis of the target.  Results:  It was found that the sensors were very useful when 2-3 nanoparticles were used together, and it showed that in between stage 1 and 2 CKD with an accuracy of 60% and in between stage 4 and stage 5 of CKD accuracy was 67%. There were various substances in breath which could identify many toxins which were accumulated due to kidney function loss. Read more about articles:  https://lupinepublishers.com/clinical-community-medicine/fulltext/gold-nanoparticle-sensor-for-the-detection-of-ckd-and-use-of-nanomedicine.ID.000109.php Read more L...

Lupine Publishers | Journal of Clinical and Community Medicine Abstract Introduction & Objectives: Short penile length is probably the oldest symptom of men for centuries. It can be troubling enough for many men although not short in fact. Urologists often meet cases attending with complaints of insufficient penile length, but it is known that the measures of penile length are normal in majority of cases. It is known that nearly all of the cases do not have any knowledge in terms of normal penile length. In the literature, many studies have dealt with measures of penile length in flaccid position. In order to build up a nomogram of the population, erectile penile length and penile circumference should be measured. Material & Methods: In this study, cases attending with complaints of insufficient penile length and/or penile curvature were evaluated retrospectively via results of self-measurement of erectile penile length by photographs taken by the patients at home and circumfer...

Lupine Publishers | Journal of Clinical and Community Medicine Short Communication Evidence-based clinical practice emphasizes the use of information from well designed and conducted research in healthcare decision-making. It largely depends upon the outcomes from prospective randomized clinical trials in which the number of patients are sufficiently high to ensure that the results are robust. Such trials need to be adequately powered and to define from the beginning what magnitude of difference between treatments is being sought. The classical approach when assessing the value of new medications has been the use of blind assessments in which both patients and assessors do not know which drug or placebo they are receiving. The application of such an approach in Al-Hijama is either impractical or even unethical as it would require use of sham wet cupping. A recent review from Iran Bamfarahnak et al. [1] suggested Al-Hijama is currently prescribed for up to 120 diseases that are difficul...